Mr Leon Almashan
Clinically Reviewed By: Mr Leon Almashan , BSc (Hons), Lead Medical Consultant
HCPC: PH80026 | ISSM: M.37761
Last clinically reviewed: 19 October 2026

Meet Our Peyronie's Disease Specialists

Every NanoVi® treatment recommendation follows a comprehensive clinical assessment by our specialist team. We take the time to understand your symptoms, examine your condition and determine whether NanoVi Exo® could support your personalised treatment programme. Our priority is providing honest, clinically informed advice based on your individual diagnosis, whether NanoVi is recommended alongside focused shockwave therapy, EMTT or another non-surgical treatment option.

Clinical Expertise, Supported by Lived Experience

Our team understands Peyronie’s disease from both a clinical and personal perspective. Alongside our experienced medical professionals, Charles brings first-hand experience of living with the condition for 17 years and undergoing two surgical procedures. His lived experience offers valuable insight into the physical and emotional challenges patients may face, helping those considering NanoVi® and other non-surgical treatments feel understood, informed and supported throughout their journey.

Why Choose Man's Matters for NanoVi Therapy Peyronie's Disease Treatment

Peyronie’s disease is a complex condition, and every patient experiences it differently. At Mans Matters, we combine specialist clinical experience, advanced NanoVi Exo® technology and a thorough individual assessment to create a personalised treatment programme based on your symptoms, diagnosis and overall needs.

✓ 6,000+ men treated in our London clinic. 

✓ Non-invasive treatment with no downtime.

✓ Internationally recognised clinicians.

✓ Presented award-winning research internationally.

Focused Shockwave Therapy

Peyronie’s Disease: More Common Than You Might Think

3% to 10%
of men are estimated to experience Peyronie’s disease
Peyronie’s disease may be more common than many men realise. NanoVi® can be incorporated into a personalised, non-invasive programme designed to support the body’s natural cellular repair processes.
4×
more powerful than the NanoVi Eco® model
Mans Matters uses the advanced NanoVi Exo®, the most powerful device in the NanoVi range, alongside other elements of a personalised Peyronie’s disease treatment programme.

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Our Expert Peyronie's Disease NanoVi Machinery

Our specialist Knightsbridge clinic is equipped with the NanoVi Exo®, the newest and most powerful device in the NanoVi® range. Our experienced team uses this advanced, non-invasive technology to support the body’s natural cellular repair processes as part of a personalised treatment programme for Peyronie’s disease.

NanoVi® Exo Therapy

NanoVi Exo® Cellular Repair Technology

Our clinicians use the NanoVi Exo®, the newest and most powerful device in the NanoVi® range. It is twice as powerful as the NanoVi Pro® and four times as powerful as the NanoVi Eco®, providing a higher level of output within a shorter session.

For comparison, 15 minutes with the NanoVi Exo® provides the equivalent device output of 30 minutes with the Pro or 60 minutes with the Eco. This allows NanoVi therapy to be delivered efficiently alongside Focused Shockwave Therapy (f-ESWT) or EMTT as part of a personalised Peyronie’s disease treatment programme.

Most Powerful NanoVi® Model.

Non-Invasive and Comfortable.

Can Be Combined With Other Treatments.

Visit Our London Peyronie's Disease NanoVi Therapy Clinic

✓ 2 minutes from Harrods.

✓ 5 minutes from Knightsbridge Station.

If you are considering NanoVi® therapy for Peyronie’s disease in London, our specialist team in Knightsbridge provides confidential assessments and personalised treatment programmes based on your individual condition and needs.

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Real Patient Success Stories

I had Peyronie’s Disease for 3 years. I was depressed thinking is this it, am I gonna live with this. My erections were poor, my curvature was 45 degrees to the left side and 40 degrees up. My relationship suffered. But the results were great. I did the PD360 here; my penis improved, no more erection problems, in fact it’s 100% better. And curvature to the left side is no more and upward 30 degrees. My partner noticed sex is better, harder erections, longer lasting and it doesn’t slip out anymore. It helped restore my relationship and confidence. I am glad I didn’t just accept it or do surgery.

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Who is NanoVi Therapy Suitable For?

NanoVi® therapy can form part of a personalised, non-invasive treatment programme for Peyronie’s disease. Before making a recommendation, our specialist team will assess your symptoms, medical history and individual diagnosis to determine whether NanoVi® could play an appropriate supporting role within your wider treatment plan.

✓

Men With Peyronie’s Disease

NanoVi® may be considered for men seeking a non-invasive approach that supports the body’s natural cellular repair processes.

✓

Patients Receiving Combined Treatment

NanoVi® can be delivered alongside Focused Shockwave Therapy (f-ESWT) or EMTT as part of a wider, personalised treatment programme.

✓

Those Seeking Non-Invasive Support

Treatment does not require injections or surgery, making it suitable for patients exploring non-invasive treatment options.

✓

Patients Assessed by Our Clinicians

Suitability depends on your symptoms, medical history and diagnosis, which our clinical team will review before making a recommendation.

NanoVi® is not presented as a standalone cure for Peyronie’s disease. Our team will explain whether it could play a suitable supporting role within your individual treatment programme.

How Can Peyronie's Disease Change the Shape of the Penis?

Peyronie’s disease can change the shape of the penis in several ways, with curvature being only one possible presentation. Some men may experience narrowing, indentation, an hourglass shape or reduced stability during an erection. Identifying the nature and extent of these changes helps our specialist team assess your condition and determine whether NanoVi® could play a supporting role alongside other therapies within your personalised treatment programme.

01
Penile Curvature

One of the most recognised signs of Peyronie’s disease is a new or worsening bend in the penis. The curvature may develop upwards, downwards or to either side and can vary considerably between patients.

02
Hourglass Deformity

An hourglass deformity occurs when part of the penile shaft becomes narrower, creating a pinched or hourglass-like appearance during an erection.

03
Indentation

Some men develop a visible indentation or dip along one side of the penile shaft. This can create an uneven appearance and may occur alongside curvature or narrowing.

04
Hinge Effect

The hinge effect describes an area of reduced stability where the penis may bend or buckle during an erection, potentially making sexual intercourse more difficult.

05
Penile Shortening

The tissue changes associated with Peyronie’s disease can sometimes cause a noticeable reduction in penile length. The extent and impact of shortening differ between individuals.

06
Penile Narrowing

Narrowing may affect a specific area of the penile shaft and can develop alongside other changes, including indentation, curvature or an hourglass deformity.

Where NanoVi® may fit into treatment: NanoVi® does not act directly on penile curvature or deformity. Instead, it may be used to support the body’s natural cellular repair processes alongside treatments that more directly address the symptoms and tissue changes associated with Peyronie’s disease.

NanoVi Therapy for Peyronie's Disease Treatment Pricing

We believe in being clear and transparent about treatment costs. NanoVi Exo® is included within selected multimodal treatment programmes for Peyronie’s disease rather than offered as a standalone treatment, with recommendations based on your individual assessment, symptoms and clinical needs.
In-Clinic Consultation
A private consultation with a men’s health specialist to assess your condition and discuss whether a treatment programme including NanoVi Exo® may be suitable.
£150 Specialist clinical assessment
Includes NanoVi Exo®
Standard Peyronie’s Disease Package
A six-session multimodal programme combining three non-invasive therapies for Peyronie’s disease.
  • Advanced Focused Shockwave Therapy (f-ESWT)
  • EMTT
  • NanoVi Exo®
£2,995 Six treatment sessions
Standard Combined PD and ED Package
A combined six-session programme for men experiencing Peyronie’s disease alongside erectile dysfunction.
  • Advanced Focused Shockwave Therapy (f-ESWT)
  • EMTT
  • NanoVi Exo®
£3,995 Six treatment sessions
Need some guidance?
Not Sure Which Package Is Right for You?
You do not need to choose a package yourself. Our specialist team will assess your symptoms and explain whether NanoVi Exo® should form part of your personalised treatment programme.
Please note: NanoVi Exo® is included as part of a combined treatment programme rather than priced as a standalone treatment. The most appropriate package will be recommended following your clinical assessment.
Book a Free Phone Consultation now

Take the Peyronie's Disease Test

Answer a few simple questions. This test is for informational purposes only and not a substitute for professional medical advice.

 

Quiz clinically reviewed by Mr Leon Almashan

Lead Medical Consultant & Joint Managing Partner

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How We Diagnose Peyronies Disease

We do not believe in a one-size-fits-all approach. Before recommending NanoVi® or incorporating it into a wider treatment programme, our experienced clinicians conduct a thorough assessment to understand your condition, evaluate your symptoms and determine the most appropriate combination of therapies for your individual needs.

1. Initial Enquiry

Your journey begins with a confidential enquiry to our specialist team. We’ll listen to your concerns, answer any initial questions and explain what to expect from your consultation, helping you decide whether an assessment at our Knightsbridge clinic is the right next step.

Before your clinic visit, you’ll have the opportunity to discuss your symptoms with a member of our experienced team. This confidential conversation helps us understand your concerns, answer your questions and ensure you are booked into the most appropriate consultation.

During your appointment, our specialist team will discuss your symptoms, medical history and how your condition has developed. We also consider factors such as erectile function, current medications, diet, lifestyle and any other health conditions that may be relevant, helping us build a more complete understanding of your individual circumstances.

A private physical examination allows our specialist to assess the location and presentation of plaque and any changes to the shape of the penis. This can include the direction and degree of curvature, hourglass deformity, indentation, narrowing, hinge effects and shortening, helping us understand how Peyronie’s disease is presenting in your individual case.

Using the information gathered during your consultation and examination, our specialist team will assess the presentation and stage of your Peyronie’s disease, including whether it appears to be in the acute or chronic phase. We will explain our findings clearly, discuss how the condition is affecting you and answer any questions before recommending treatment.

Following your assessment, we’ll recommend a personalised treatment plan based on your diagnosis, symptoms and goals. If focused shockwave therapy is the right option for you, we’ll explain how it works and what results you may be able to expect. If another treatment would be more appropriate, we’ll explain this honestly and discuss the available alternatives.

Once you’re happy to proceed, your treatment will begin at our specialist Knightsbridge clinic. Every session is delivered by experienced clinicians using advanced focused shockwave technology, with your progress monitored throughout your treatment to ensure the best possible outcome.

I’m 18 or older

Focused Shockwave Therapy 3

Book a Private Consultation Today

If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.

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NanoVi therapy for Peyronie's disease

How Does NanoVi Therapy Work?

NanoVi® therapy is simple, non-invasive and requires no injections or surgery. You remain seated and breathe normally while the NanoVi Exo® supports the natural processes your body uses to repair damaged cells.

01
Get Comfortable

You sit comfortably while a member of our team prepares the NanoVi Exo® device.

02
The Nasal Tube Is Fitted

A small, lightweight tube is placed beneath your nose. There are no needles, injections or surgery.

03
Breathe Normally

The tube delivers humidified air from the device. You simply relax and breathe as normal.

04
Natural Repair Is Supported

The air carries signals designed to support the natural processes your body uses to repair damaged cells.

Benefits of NanoVi Therapy for Peyronie’s Disease

NanoVi® therapy provides a non-invasive treatment option that can support the body’s natural cellular repair processes, with no surgery, injections or lengthy recovery period required.

✓ Supports Natural Cellular Repair.

✓ Helps Body Respond to Oxidative Stress.

✓ Supports Healthy Protein Function.

✓ Completely Non-Invasive.

✓ Comfortable and Easy to Receive.

✓ Can Complement Other Treatments.

I’m 18 or older

NanoVi Exo 4

Real Patient Success Stories

Very happy with my experience at the clinic and the staff. The clinic itself is very well kept and clean and the doctors/staff are very friendly and knowledgable providing me with all the information, and more, that I could possibly need with regards to my specific case. Overall very satisfied with my experience and would recommend to anyone with similar struggles/conditions.

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Acute and Chronic Peyronie's Disease Compared

Peyronie’s disease can develop differently from one person to another, and understanding whether the condition is in its acute or chronic stage is an important part of your assessment. Each stage can present different symptoms and changes, which our specialist team considers when discussing the most appropriate treatment options for you.

Early Stage
Acute Peyronie’s Disease
The acute phase is the earlier, active stage of Peyronie’s disease, when symptoms may still be developing or changing over time.
  • Penile curvature may still be changing
  • Pain or discomfort may be present, particularly during erections
  • Plaque and scar tissue may still be developing
  • Changes in shape, indentation or hourglass deformity may appear
  • Erectile function may also be affected
During assessment, our specialist team will consider how long your symptoms have been present and whether your condition is still changing before recommending treatment.
Stable Stage
Chronic Peyronie’s Disease
The chronic phase is generally considered the more stable stage, when the curvature and other changes have stopped progressing.
  • Penile curvature is typically more stable
  • Pain may have reduced or resolved
  • Plaque and scar tissue are usually established
  • Deformities such as bends, indentation or hourglass narrowing may remain
  • Erectile dysfunction can continue alongside the condition
Understanding whether Peyronie’s disease is acute or chronic helps our clinicians assess your condition and discuss the treatment options that may be most appropriate for you.

Peyronie's Disease Treatment Options Explained

Understanding your treatment options can help you feel more confident about your next steps. In this video, we explain Peyronie’s disease and focused shockwave therapy, including how the treatment works and the role it may play within a wider treatment approach.

Every case of Peyronie’s disease is different, which is why our specialists carry out an individual clinical assessment before recommending the most appropriate treatment plan for you.

 All Peyronie’s Disease Treatment Options

Award-Winning Research Advancing Peyronie's Disease Treatment

Our specialist team doesn’t just treat Peyronie’s disease. We’re actively contributing to research into non-surgical treatment. Our PD360 research was presented at a major international urology conference in Dubai, where it was selected as the top submission from approximately 150 entries, recognising the work being carried out to advance understanding of Peyronie’s disease treatment.

pd leon

Our clinical team is actively contributing to research into non-surgical approaches to Peyronie’s disease. Our PD360 research was presented at a major international urology conference in Dubai, where it was selected as the top submission from approximately 150 entries.

The research examines patient outcomes from a comprehensive, multimodal approach to Peyronie’s disease treatment and is currently progressing through the peer-review process.

For our patients, this commitment to research means treatment recommendations are informed not only by years of specialist clinical experience, but by an ongoing drive to better understand Peyronie’s disease and the treatment options available.

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Book a Private Consultation Today

If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.

Book a Free Phone Consultation now

FAQs

Peyronie’s NanoVi Therapy FAQ’s

NanoVi® is a non-invasive therapy designed to support the body’s natural cellular repair processes. During treatment, the NanoVi Exo® produces a stream of humidified air carrying specific biological signals. You breathe this air normally through a small nasal tube while sitting comfortably.

The NanoVi Exo® applies specific electromagnetic signals to humidified air, which is then delivered through a small nasal tube. These signals are designed to support healthy protein activity and the processes the body naturally uses to repair damaged cells and respond to oxidative stress.

NanoVi® supports the body’s natural cellular repair processes. At Mans Matters, it can be incorporated alongside therapies such as Focused Shockwave Therapy (f-ESWT) and EMTT to provide a broader treatment approach based on the patient’s symptoms, diagnosis and individual clinical needs.

NanoVi® may provide cellular repair support within a personalised programme addressing the symptoms and tissue changes associated with Peyronie’s disease. Our clinicians assess penile curvature, plaque, narrowing, indentation, discomfort and erectile function before recommending the most appropriate combination of treatments.

Each therapy performs a different role within the treatment programme. NanoVi® supports natural cellular repair, while Focused Shockwave Therapy (f-ESWT) and EMTT provide more targeted support to the affected tissues. Combining these approaches allows our clinicians to create a more comprehensive programme for each patient.

NanoVi Exo® is included within the clinic’s six-session multimodal programmes for Peyronie’s disease. The recommended number and combination of treatments will depend on your symptoms, diagnosis and clinical assessment. Your treatment plan and costs will be explained clearly before you begin.

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