This page  explores the history of Peyronie’s Disease and reviews various medical therapies, including surgical treatments, that have been used to address it along with their expected outcomes. We also examine modern, non-invasive treatment options that are available today for managing Peyronie’s Disease.

History of Peyronie's Disease

Exploring the Historical Evolution of Peyronie's Disease

Peyronie’s Disease, also known as Induratio Penis Plastica, has been documented in medical literature since the 1500s. Early references appear in the works of renowned anatomists like Gabriel Fallopius, a pioneer in the study of reproductive organs, and Andreas Vesalius, the 16th-century Dutch physician whose seminal book De Humani Corporis Fabrica Libri Septem (On the Fabric of the Human Body) greatly influenced anatomical studies.

 In 1743, Francois de la Peyronie, a surgeon at the Court of King Louis XV in France, provided the first detailed description of the condition, which subsequently became known in England as ‘Peyronie’s Disease’ or simply ‘Peyronies.’

The first surgical procedure to correct Peyronie’s Disease by removing fibrous plaque was performed in 1882. It wasn’t until 1943 that significant advancements were made, when Mr. O.S. Lowsley removed plaque and introduced new tissue to the affected area. In 1965, R. Nesbit pioneered a ‘tucking’ technique, which became popular despite often reducing penile length by up to 8 cm (3 inches).

Evolution of Peyronie's Disease Treatments

Recent treatments for Peyronie’s Disease have included options such as Xiapex injections, penile plication (a procedure that shortens the penis), and penile implants. Penile implants allow an erection to be achieved with the help of a manual pump. For more information, please visit our page on Peyronie’s Disease Treatment Options.

Today, Focused Shockwave Treatment (FSWT) is widely regarded by leading practitioners as a primary non-invasive option for managing Peyronie’s Disease.

FSWT offers patients a non-surgical approach, reducing the need for invasive procedures. The shockwaves help to address fibrous plaque, which the body may process and eliminate naturally. Many patients report improvements in curvature and physical function following treatment, supporting overall well-being.

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