Clinically Reviewed By: Mr Leon Almashan, Lead Medical Consultant and Joint Managing Partner

Visit Our London Peyronie's Disease Treatment Clinic

2 minutes from Harrods.

✓ 5 minutes from Knightsbridge Station.

If you are looking for a specialist Peyronie’s disease treatment clinic, our experienced Knightsbridge team provides confidential assessments and personalised treatment plans based on your symptoms, disease stage and individual needs.

Our Peyronie's Disease Treatments Compared

Peyronie’s disease treatment is not one size fits all. The options recommended will depend on your disease stage, plaque, curvature, pain, erectile function, medical history and the effect the condition is having on your life.

Treatment or Programme What It Involves Treatment Format How It Is Available
Multimodal Peyronie’s Programme A coordinated programme combining Focused Shockwave Therapy, Magnetolith EMTT and NanoVi ExO. Non-invasive treatment delivered across a structured clinic programme. One of our core treatment pathways, personalised following a clinical assessment.
PD360 Our comprehensive clinician-led Peyronie’s disease programme, which may bring together different treatment approaches according to individual clinical needs. Personalised multimodal programme with the course determined following assessment. One of our core treatment pathways for men requiring a more comprehensive approach.
Focused Shockwave Therapy Targeted acoustic waves are delivered using the Duolith SD1 T-Top and specialist C-Actor handpiece. Treatment settings are selected following assessment. Non-invasive treatment delivered during clinic sessions. Used as one of the three technologies within our multimodal treatment programme.
Magnetolith EMTT High-energy magnetic pulses are delivered to the treatment area as a complementary component of multimodal care. Non-invasive and delivered in the clinic. Included within the multimodal programme and not offered separately.
NanoVi ExO A non-invasive breathing-based supportive technology used alongside Focused Shockwave Therapy and EMTT. Non-invasive and delivered in the clinic. Included within the multimodal programme and not offered as a standalone Peyronie’s treatment.
EMDA Electromotive Drug Administration uses a controlled electrical current to support the targeted delivery of prescribed medication into the plaque. Non-surgical prescription treatment delivered in the clinic. Available following a clinical assessment and review by a qualified men’s health prescriber.
SOMAcorrect Medical Vacuum Pump A medical vacuum device that uses controlled negative pressure as part of an individually recommended home-use protocol. Non-invasive medical device for home use. Supplied with individual in-clinic fitting and training covering positioning, pressure, duration and safe use.
RestoreX Penile Traction A specialist traction device that applies controlled mechanical stretching according to an individual usage plan. Non-invasive medical device for home use. Supplied with in-clinic fitting and guidance covering positioning, tension, duration and safe use.
Medication and Injection Therapies Medication or injection-based approaches may be considered depending on disease stage, symptoms, medical history and treatment availability. The format varies according to the treatment prescribed or recommended. Discussed following an individual clinical assessment, including expected benefits, limitations and alternatives.

Which Peyronie's Disease Treatment is Right for Me?

Treatment recommendations depend on the stage of the condition, whether your symptoms are still changing and how they affect your comfort, erections and sexual function.

New or changing symptoms

Acute or Active Peyronie’s Disease

This stage is generally associated with recent symptoms, pain or continuing changes to penile shape and curvature.

Signs that may apply to you

  • Curvature is new or worsening
  • Pain occurs during erections
  • A plaque or lump has developed
  • Shape or length is changing
Non-surgical treatment EMDA Vacuum therapy Traction Monitoring
Symptoms are no longer changing

Chronic or Stable Peyronie’s Disease

The stable stage may be reached when curvature has stopped changing and pain has reduced or disappeared.

Signs that may apply to you

  • Curvature has remained stable
  • Pain has reduced or stopped
  • Plaque may be established or calcified
  • Shortening or indentation remains
Multimodal programme Vacuum therapy Traction Injection therapies Surgical opinion
Significant functional impact

Complex or Severe Peyronie’s Disease

More complex presentations require a detailed assessment of the deformity, plaque and erectile function.

Signs that may apply to you

  • Severe or multiplanar curvature
  • Hourglass deformity or indentation
  • Multiple plaques or calcification
  • Intercourse is difficult or impossible
Specialist assessment Multimodal treatment Erectile function support Medical devices Surgical referral

You Do Not Need to Select a Treatment Yourself

A specialist assessment considers your disease stage, curvature, plaque, pain, erectile function, medical history and previous treatment before a recommendation is made.

This information is a general guide and cannot determine your diagnosis, disease stage or treatment suitability. An individual clinical assessment is required.

Real Patient Success Stories

I came across Mansmatters online, as I was frustrated with my local hospital, not much care and dismissed it. I found Mansmatters friendly and professional. I did the PD360 protocol injections for my Peyronie’s disease and after my fourth injections, I’ve seen 40% improvement to my curvature and erections 100%. I highly recommend Mansmatters.

Meet Our Peyronie's Disease Specialists

Every treatment recommendation is made following a comprehensive clinical assessment by our specialist team. Rather than taking a one-size-fits-all approach, we assess your symptoms, examine your condition and recommend the treatment that is most appropriate for you. Our priority is providing honest, personalised advice based on your individual diagnosis, whether that involves focused shockwave therapy or an alternative treatment option.

Leon Almashan

Leon Almashan

Lead Medical Consultant & Joint Managing Partner

Charles Turner

Charles Turner

Practice Director & Joint Managing Partner

Dr Anthony Harding

Dr Anthony Harding

Medical Consultant

Stefan Anastasescu

Stefan Anastasescu

Urology Specialist

Joshua Hearne Wilkins

Joshua Hearne-Wilkins

Urology Specialist

Clinical Expertise, Supported by Lived Experience

Our team understands Peyronie’s disease from both a clinical and personal perspective. Alongside our experienced medical professionals, Charles brings first-hand experience of living with Peyronie’s disease for 17 years and undergoing two surgical procedures. This lived experience provides a valuable understanding of the questions, concerns and emotional impact that can come with the condition, helping patients feel understood and supported throughout their journey.

Focused Shockwave Therapy for Peyronie's Disease

Focused Shockwave Therapy delivers targeted acoustic waves into fibrotic penile tissue, stimulating a local regenerative response and supporting blood flow and tissue recovery.

Unlike radial wave devices, focused technology allows deeper penetration and more precise targeting of affected areas. Treatment is delivered across multiple sessions as part of a personalised treatment programme.

Available in £1,995 and £2,995 Programmes
Treatment Type Non-surgical
Typical Course Six clinic sessions
Anaesthetic Usually not required
Technology Duolith SD1 C-Actor
Duolith SD1 T-Top focused shockwave system with C-Actor handpiece

Duolith SD1 T-Top With C-Actor Handpiece

Our clinicians use advanced STORZ MEDICAL technology to deliver precise, focused shockwaves to selected treatment areas.

The system offers an energy range of 0.01 to 0.55 mJ/mm², while the specialist C-Actor handpiece extends this up to 1.24 mJ/mm². Treatment depth, energy and location are selected following an individual assessment.

Precise, Focused Delivery

Adjustable Treatment Depth

Specialist C-Actor Handpiece

Magnetolith EMTT equipment used within multimodal Peyronie's disease treatment

Magnetolith EMTT

Magnetolith uses Extracorporeal Magnetotransduction Therapy, delivering high-energy magnetic pulses to the treatment area.

The system operates at an oscillation frequency of up to 3 kHz and a magnetic field strength of up to 100 mT. It may be used alongside Focused Shockwave Therapy where clinically appropriate.

High-Frequency Magnetic Pulses

High-Intensity Magnetic Field

Supports Multimodal Treatment

Peyronie's Disease Guidance from Leading Professional Bodies

Peyronie’s disease is recognised by leading urological and sexual medicine organisations around the world. These professional bodies review clinical evidence, publish guidance and provide information to support informed conversations between patients and appropriately qualified healthcare professionals.

BAUS
British Association of Urological Surgeons

BAUS represents urological surgeons in the UK and provides dedicated patient information about Peyronie’s disease, its assessment and the available treatment routes.

Read the BAUS patient information
EAU
European Association of Urology

The EAU publishes evidence-based clinical guidance covering the diagnosis and conservative and surgical management of Peyronie’s disease and penile curvature.

View the EAU clinical guidance
AUA
American Urological Association

The AUA publishes clinical guidance to help healthcare professionals assess Peyronie’s disease, discuss treatment choices and counsel patients about expected outcomes.

Explore the AUA guideline
ISSM
International Society for Sexual Medicine

The ISSM supports professional education and the sharing of research across sexual medicine, including developments relating to Peyronie’s disease and male sexual health.

Visit the ISSM website

These organisations provide independent professional guidance and educational information. Their inclusion does not imply approval, accreditation or endorsement of our clinic or any particular treatment. Recommendations at our clinic are made following an individual clinical assessment, with potential benefits, limitations and alternative treatment options discussed before treatment.

Peyronie's Disease Treatment Pricing

We believe in being clear and transparent about the cost of treatment. Our Peyronie’s disease treatment options range from specialist consultations to focused shockwave and multimodal treatment programmes, with recommendations based on your individual assessment, symptoms and clinical needs.

In-Clinic Consultation
A private in-clinic consultation with a Men's Health specialist to assess your condition and discuss the most appropriate treatment options.
£150
Peyronie's Penile Pump
A specialist penile pump supplied with full training to help you understand how to use it safely and correctly.
£350
Multimodal Peyronie's Disease Treatment
A combined treatment approach incorporating focused shockwave therapy, Electromagnetic Transduction Therapy and NanoVi ExO where clinically appropriate.
£2,995
PD360
Our most comprehensive non-surgical Peyronie's disease treatment programme, bringing together multiple treatment approaches within one personalised pathway.
£5,500 Comprehensive treatment programme
Need some guidance?
Not Sure Which Treatment Is Right for You?
You don't need to decide on a treatment yourself. Speak confidentially with our specialist team about your symptoms, concerns and the options that may be suitable for you.
Electromagnetic Transduction Therapy

Extracorporeal Magneto Transduction Therapy (EMTT)

Treatment Type Non-invasive
Typical Course Six clinic sessions
Anaesthetic Not required
Technology Magnetolith EMTT

Extracorporeal Magnetotransduction Therapy, or EMTT, is a non-invasive treatment that delivers high-energy magnetic pulses into the treatment area to support cellular activity, circulation and tissue recovery. At our clinic, EMTT may be used alongside Focused Shockwave Therapy as part of a personalised multimodal programme. Treatment suitability and settings are determined following an individual clinical assessment.

Book a Private Consultation Today

If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.

NanoVi Exo

Treatment Type Non-invasive supportive therapy
Typical Course Six clinic sessions
Anaesthetic Not required
Technology NanoVi Exo

NanoVi Exo is a non-invasive supportive therapy designed to support the body’s natural response to oxidative stress and cellular repair. During a session, the patient breathes normally through a nasal cannula while the system delivers a humidified air stream carrying a structured-water signal. At our clinic, NanoVi Exo is used alongside Focused Shockwave Therapy and EMTT within the £2,995 multimodal programme. It is not offered as a standalone treatment for Peyronie’s disease.

NanoVi Exo
Focused Shockwave Therapy 2

PD360

Treatment Type Non-surgical technology and injection treatment
Appointment Time Approximately one hour
Assessment Required before treatment
Treatment Process Several technologies alongside blood processing, prescription drugs* and photoactivation.

PD360 is a comprehensive, non-surgical treatment protocol for Peyronie's Disease that combines a number of specialists technologies with clinician prescribed medication* and regenerative platelet therapy. Focused sound waves break down plaque and calcium deposits, while targeted technologies address inflammation, blood flow, oxidative stress and abnormal collagen. Platelets, drawn from your own blood and enriched with growth factors, are precisely injected alongside medication around the affected area. Supervised home devices and lifestyle guidance help maintain results between sessions. Suitability, potential benefits and limitations are discussed during clinical assessment, and results vary between patients.

*Any prescription-only medication used as part of the PD360 treatment is prescribed by an appropriately qualified prescriber following clinical assessment.

Medical Vacuum Pumps

Treatment Type Non-invasive home therapy
Training Personal in-clinic instruction
Anaesthetic Not required
Medical Device SOMAcorrect vacuum pump

Medical vacuum therapy uses controlled negative pressure to draw blood into the penis, supporting circulation, tissue expansion and flexibility. The SOMAcorrect medical vacuum pump is supplied with full in-clinic fitting and personalised training on pressure, positioning, treatment duration and safe use. Although similar devices may be available online, professional instruction helps patients use the pump correctly as part of their individual Peyronie’s disease treatment plan.

Peyronie's Disease and Medical Vacuum Pumps

Peyronie's Disease Surgery

At MansMatters, we offer non-invasive treatments designed to treat Peyronie’s disease by improving blood flow, breaking down scar tissue and enhancing erectile function. Unlike surgical procedures, our multi-modal approach aims to restore natural function without the risks associated with invasive treatments.

Implants

Implants are a treatment option for severe cases of Peyronie’s Disease, particularly for patients who may also experience erectile dysfunction (ED). The implant is surgically inserted into the penis and is operated by a mechanical pump, allowing the user to achieve an erection when desired. It is important to note that while implants can provide a functional solution for achieving rigidity, they may affect the ability to achieve natural erections, and sensitivity and length may vary based on the type of prosthesis used. Patients should discuss with their healthcare provider to understand the benefits and limitations of this treatment option.

5 illustration Cross section of peyronies

Surgical Graft

 Surgical grafting is a procedure typically considered for men with complex or severe curvature of Peyronie’s Disease. This surgery is performed at a stable stage of the condition. The procedure involves excising the fibrous plaque and replacing it with a graft, which can be made from animal or synthetic materials to fill the resulting gap. During the surgery, the nerves near the penis and urethra may be carefully mobilized to minimize disruption and are reconnected at the end of the procedure. The goal of this surgery is to improve curvature and restore function, offering a potential solution for those with significant symptoms.

The journal Translational Andrology & Urology advises that patients considering surgical grafts for Peyronie’s Disease should be informed about potential adverse effects and outcomes. These may include persistent or recurrent curvature, changes in sensation, altered erectile function, or possible penile shortening

Surgical graft

Surgery – Plication

Plication, or the Nesbitt technique, is typically considered for patients with moderate curvature of less than 60 degrees who do not experience erectile dysfunction. This procedure is performed during the stable chronic phase of Peyronie’s Disease. It involves shortening the longer side of the penis to align with the side affected by fibrous plaque. Patients may experience a reduction in overall length, which can be significant, with reports of shortening by several centimeters.

While many patients find this surgery beneficial for correcting curvature, it is important to discuss potential outcomes, including the possibility of changes in penile length and discomfort from sutures used during the procedure.

plication

Peyronie’s Disease: More Common Than You Might Think

3–10%
of men are estimated to experience Peyronie's disease
Peyronie's disease may be more common than many men realise, with estimates suggesting it affects between 3% and 10% of men.
28%
of patients may experience erectile dysfunction alongside Peyronie's disease
Erectile dysfunction can occur alongside or after Peyronie's disease develops, which is why sexual function forms an important part of a specialist assessment.

Book a Private Consultation Today

If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.

FAQs

Frequently Asked Questions

The best treatment depends on the stage and severity of the condition. At our London clinic, we use a combination of non-surgical therapies, including focused shockwave therapy, EMTT, NanoVi Exo and medical vacuum pumps to support structural recovery and reduce curvature.

Focused shockwave therapy can help reduce plaque formation, improve blood flow and alleviate discomfort. It is most effective in stable-phase Peyronie’s and is often used alongside other regenerative technologies.

Yes. Many men respond well to conservative, non-invasive therapies when treatment is started early. Our approach avoids surgical risks while addressing curvature and function through advanced physical and regenerative modalities.

Medical vacuum devices support tissue stretching and improve circulation. They are commonly used to maintain or enhance gains achieved through other non-surgical treatments and may assist with penile flexibility.

If left untreated, Peyronie’s disease may stabilise or progress, leading to worsening curvature, discomfort and potential erectile dysfunction. Early clinical assessment allows for timely, non-surgical intervention.

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