Explore non-surgical and surgical treatments for Peyronie’s disease, including which options may be considered during the acute and chronic stages. At our specialist London clinic, every treatment plan begins with a detailed assessment of your symptoms, plaque, curvature and erectile function.
✓ 2 minutes from Harrods.
✓ 5 minutes from Knightsbridge Station.
If you are looking for a specialist Peyronie’s disease treatment clinic, our experienced Knightsbridge team provides confidential assessments and personalised treatment plans based on your symptoms, disease stage and individual needs.
Peyronie’s disease treatment is not one size fits all. The options recommended will depend on your disease stage, plaque, curvature, pain, erectile function, medical history and the effect the condition is having on your life.
| Treatment or Programme | What It Involves | Treatment Format | How It Is Available |
|---|---|---|---|
| Multimodal Peyronie’s Programme | A coordinated programme combining Focused Shockwave Therapy, Magnetolith EMTT and NanoVi ExO. | Non-invasive treatment delivered across a structured clinic programme. | One of our core treatment pathways, personalised following a clinical assessment. |
| PD360 | Our comprehensive clinician-led Peyronie’s disease programme, which may bring together different treatment approaches according to individual clinical needs. | Personalised multimodal programme with the course determined following assessment. | One of our core treatment pathways for men requiring a more comprehensive approach. |
| Focused Shockwave Therapy | Targeted acoustic waves are delivered using the Duolith SD1 T-Top and specialist C-Actor handpiece. Treatment settings are selected following assessment. | Non-invasive treatment delivered during clinic sessions. | Used as one of the three technologies within our multimodal treatment programme. |
| Magnetolith EMTT | High-energy magnetic pulses are delivered to the treatment area as a complementary component of multimodal care. | Non-invasive and delivered in the clinic. | Included within the multimodal programme and not offered separately. |
| NanoVi ExO | A non-invasive breathing-based supportive technology used alongside Focused Shockwave Therapy and EMTT. | Non-invasive and delivered in the clinic. | Included within the multimodal programme and not offered as a standalone Peyronie’s treatment. |
| EMDA | Electromotive Drug Administration uses a controlled electrical current to support the targeted delivery of prescribed medication into the plaque. | Non-surgical prescription treatment delivered in the clinic. | Available following a clinical assessment and review by a qualified men’s health prescriber. |
| SOMAcorrect Medical Vacuum Pump | A medical vacuum device that uses controlled negative pressure as part of an individually recommended home-use protocol. | Non-invasive medical device for home use. | Supplied with individual in-clinic fitting and training covering positioning, pressure, duration and safe use. |
| RestoreX Penile Traction | A specialist traction device that applies controlled mechanical stretching according to an individual usage plan. | Non-invasive medical device for home use. | Supplied with in-clinic fitting and guidance covering positioning, tension, duration and safe use. |
| Medication and Injection Therapies | Medication or injection-based approaches may be considered depending on disease stage, symptoms, medical history and treatment availability. | The format varies according to the treatment prescribed or recommended. | Discussed following an individual clinical assessment, including expected benefits, limitations and alternatives. |
Treatment recommendations depend on the stage of the condition, whether your symptoms are still changing and how they affect your comfort, erections and sexual function.
This stage is generally associated with recent symptoms, pain or continuing changes to penile shape and curvature.
Signs that may apply to you
The stable stage may be reached when curvature has stopped changing and pain has reduced or disappeared.
Signs that may apply to you
More complex presentations require a detailed assessment of the deformity, plaque and erectile function.
Signs that may apply to you
A specialist assessment considers your disease stage, curvature, plaque, pain, erectile function, medical history and previous treatment before a recommendation is made.
This information is a general guide and cannot determine your diagnosis, disease stage or treatment suitability. An individual clinical assessment is required.
I came across Mansmatters online, as I was frustrated with my local hospital, not much care and dismissed it. I found Mansmatters friendly and professional. I did the PD360 protocol injections for my Peyronie’s disease and after my fourth injections, I’ve seen 40% improvement to my curvature and erections 100%. I highly recommend Mansmatters.
Every treatment recommendation is made following a comprehensive clinical assessment by our specialist team. Rather than taking a one-size-fits-all approach, we assess your symptoms, examine your condition and recommend the treatment that is most appropriate for you. Our priority is providing honest, personalised advice based on your individual diagnosis, whether that involves focused shockwave therapy or an alternative treatment option.
Clinical Director & Men’s Health Specialist
Practice Director & Joint Managing Partner
Medical Consultant
Urology Specialist
Urology Specialist
Our team understands Peyronie’s disease from both a clinical and personal perspective. Alongside our experienced medical professionals, Charles brings first-hand experience of living with Peyronie’s disease for 17 years and undergoing two surgical procedures. This lived experience provides a valuable understanding of the questions, concerns and emotional impact that can come with the condition, helping patients feel understood and supported throughout their journey.
Focused Shockwave Therapy delivers targeted acoustic waves into fibrotic penile tissue, stimulating a local regenerative response and supporting blood flow and tissue recovery.
Unlike radial wave devices, focused technology allows deeper penetration and more precise targeting of affected areas. Treatment is delivered across multiple sessions as part of a personalised treatment programme.
Our clinicians use advanced STORZ MEDICAL technology to deliver precise, focused shockwaves to selected treatment areas.
The system offers an energy range of 0.01 to 0.55 mJ/mm², while the specialist C-Actor handpiece extends this up to 1.24 mJ/mm². Treatment depth, energy and location are selected following an individual assessment.
Precise, Focused Delivery
Adjustable Treatment Depth
Specialist C-Actor Handpiece
Magnetolith uses Extracorporeal Magnetotransduction Therapy, delivering high-energy magnetic pulses to the treatment area.
The system operates at an oscillation frequency of up to 3 kHz and a magnetic field strength of up to 100 mT. It may be used alongside Focused Shockwave Therapy where clinically appropriate.
High-Frequency Magnetic Pulses
High-Intensity Magnetic Field
Supports Multimodal Treatment
Published research has examined the use of high-energy shockwave therapy for men with chronic-phase Peyronie’s disease, including its potential effects on penile curvature, pain and sexual function.
A 2024 long-term study published in the World Journal of Urology followed 85 men who received high-energy shockwave therapy for chronic-phase Peyronie’s disease.
Curvature improved in 43 of 85 men, representing 51%. Improvement was reported in 71% of men whose starting curvature was between 30° and 60°, compared with 24% of those whose curvature was under 30°.
Pain improved in all patients treated. At long-term follow-up, 65 of 85 men, representing 76%, were reported to be completely pain-free.
Of the 59 men who reported difficulty with intercourse before treatment, 40, representing 68%, reported an improvement afterwards.
Source: Rassweiler J, Scheitlin W, Goezen AS and Radecke F. “Long-term experiences with high-energy shock wave therapy in the management of chronic phase Peyronie’s disease using two different electromagnetic lithotripters.” World Journal of Urology. 2024;42(1):124. Read the published study
These results relate to the patients, equipment and treatment methods assessed within this particular study. Individual outcomes can vary, and suitability for treatment should be determined through clinical assessment.
Peyronie’s disease is recognised by leading urological and sexual medicine organisations around the world. These professional bodies review clinical evidence, publish guidance and provide information to support informed conversations between patients and appropriately qualified healthcare professionals.
BAUS represents urological surgeons in the UK and provides dedicated patient information about Peyronie’s disease, its assessment and the available treatment routes.
Read the BAUS patient informationThe EAU publishes evidence-based clinical guidance covering the diagnosis and conservative and surgical management of Peyronie’s disease and penile curvature.
View the EAU clinical guidanceThe AUA publishes clinical guidance to help healthcare professionals assess Peyronie’s disease, discuss treatment choices and counsel patients about expected outcomes.
Explore the AUA guidelineThe ISSM supports professional education and the sharing of research across sexual medicine, including developments relating to Peyronie’s disease and male sexual health.
Visit the ISSM websiteThese independent professional sources are provided to support the clinical information on this page. Treatment recommendations at MansMatters are based on individual clinical assessment, with the potential benefits, limitations and alternatives discussed with each patient.
We believe in being clear and transparent about the cost of treatment. Our Peyronie’s disease treatment options range from specialist consultations to focused shockwave and multimodal treatment programmes, with recommendations based on your individual assessment, symptoms and clinical needs.
Leading professional organisations report that Peyronie’s disease may be more common than many men realise and can frequently occur alongside erectile dysfunction.
BAUS states that Peyronie’s disease affects approximately 1 in 16 men. As the condition may be under-reported, it notes that the true figure could be as high as 1 in 10 men.
The EAU cites studies reporting prevalence figures ranging from 0.1% to 20.3%. Differences between studies may reflect the populations assessed and the methods used to identify the condition.
The AUA guideline notes that erectile dysfunction may be present in up to 33% of patients with Peyronie’s disease. Among those men, more than half reported that erectile dysfunction began before their Peyronie’s disease symptoms.
Figures vary between studies and populations. These statistics are provided for general information and do not indicate an individual person’s likelihood of developing Peyronie’s disease or erectile dysfunction.
Extracorporeal Magnetotransduction Therapy, or EMTT, is a non-invasive treatment that delivers high-energy magnetic pulses into the treatment area to support cellular activity, circulation and tissue recovery. At our clinic, EMTT may be used alongside Focused Shockwave Therapy as part of a personalised multimodal programme. Treatment suitability and settings are determined following an individual clinical assessment.
If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.
NanoVi Exo is a non-invasive supportive therapy designed to support the body’s natural response to oxidative stress and cellular repair. During a session, the patient breathes normally through a nasal cannula while the system delivers a humidified air stream carrying a structured-water signal. At our clinic, NanoVi Exo is used alongside Focused Shockwave Therapy and EMTT within the £2,995 multimodal programme. It is not offered as a standalone treatment for Peyronie’s disease.
PD360 is a comprehensive, non-surgical treatment protocol for Peyronie's Disease that combines a number of specialists technologies with clinician prescribed medication* and regenerative platelet therapy. Focused sound waves break down plaque and calcium deposits, while targeted technologies address inflammation, blood flow, oxidative stress and abnormal collagen. Platelets, drawn from your own blood and enriched with growth factors, are precisely injected alongside medication around the affected area. Supervised home devices and lifestyle guidance help maintain results between sessions. Suitability, potential benefits and limitations are discussed during clinical assessment, and results vary between patients.
*Any prescription-only medication used as part of the PD360 treatment is prescribed by an appropriately qualified prescriber following clinical assessment.
Medical vacuum therapy uses controlled negative pressure to draw blood into the penis, supporting circulation, tissue expansion and flexibility. The SOMAcorrect medical vacuum pump is supplied with full in-clinic fitting and personalised training on pressure, positioning, treatment duration and safe use. Although similar devices may be available online, professional instruction helps patients use the pump correctly as part of their individual Peyronie’s disease treatment plan.
At MansMatters, we offer non-invasive treatments designed to treat Peyronie’s disease by improving blood flow, breaking down scar tissue and enhancing erectile function. Unlike surgical procedures, our multi-modal approach aims to restore natural function without the risks associated with invasive treatments.
Implants are a treatment option for severe cases of Peyronie’s Disease, particularly for patients who may also experience erectile dysfunction (ED). The implant is surgically inserted into the penis and is operated by a mechanical pump, allowing the user to achieve an erection when desired. It is important to note that while implants can provide a functional solution for achieving rigidity, they may affect the ability to achieve natural erections, and sensitivity and length may vary based on the type of prosthesis used. Patients should discuss with their healthcare provider to understand the benefits and limitations of this treatment option.
Surgical grafting is a procedure typically considered for men with complex or severe curvature of Peyronie’s Disease. This surgery is performed at a stable stage of the condition. The procedure involves excising the fibrous plaque and replacing it with a graft, which can be made from animal or synthetic materials to fill the resulting gap. During the surgery, the nerves near the penis and urethra may be carefully mobilized to minimize disruption and are reconnected at the end of the procedure. The goal of this surgery is to improve curvature and restore function, offering a potential solution for those with significant symptoms.
The journal Translational Andrology & Urology advises that patients considering surgical grafts for Peyronie’s Disease should be informed about potential adverse effects and outcomes. These may include persistent or recurrent curvature, changes in sensation, altered erectile function, or possible penile shortening
Plication, or the Nesbitt technique, is typically considered for patients with moderate curvature of less than 60 degrees who do not experience erectile dysfunction. This procedure is performed during the stable chronic phase of Peyronie’s Disease. It involves shortening the longer side of the penis to align with the side affected by fibrous plaque. Patients may experience a reduction in overall length, which can be significant, with reports of shortening by several centimeters.
While many patients find this surgery beneficial for correcting curvature, it is important to discuss potential outcomes, including the possibility of changes in penile length and discomfort from sutures used during the procedure.
If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.
Frequently Asked Questions
The best treatment depends on the stage and severity of the condition. At our London clinic, we use a combination of non-surgical therapies, including focused shockwave therapy, EMTT, NanoVi Exo and medical vacuum pumps to support structural recovery and reduce curvature.
Focused shockwave therapy can help reduce plaque formation, improve blood flow and alleviate discomfort. It is most effective in stable-phase Peyronie’s and is often used alongside other regenerative technologies.
Yes. Many men respond well to conservative, non-invasive therapies when treatment is started early. Our approach avoids surgical risks while addressing curvature and function through advanced physical and regenerative modalities.
Medical vacuum devices support tissue stretching and improve circulation. They are commonly used to maintain or enhance gains achieved through other non-surgical treatments and may assist with penile flexibility.
If left untreated, Peyronie’s disease may stabilise or progress, leading to worsening curvature, discomfort and potential erectile dysfunction. Early clinical assessment allows for timely, non-surgical intervention.
