Vitamin E as a treatment for Peyronie’s Disease

• 17 April 2025
• Mr. Leon Almashan

Last updated on April 25, 2025

Due to its low cost and minimal side effects, Vitamin E has often been recommended as an oral treatment for Peyronie’s Disease (PD). However, evidence regarding its effectiveness is limited, and existing studies on its efficacy are generally of low quality.

Unlocking the Potential of Vitamin E

Vitamin E is a powerful antioxidant that may help reduce free radical damage and slow aging. This fat-soluble nutrient is found in many foods and is widely available as a supplement.

In the context of treating Peyronie’s Disease (PD), Vitamin E is sometimes used for its antioxidant and anti-inflammatory properties, and it is thought to potentially reduce collagen deposits in the tunica albuginea. Early studies reported some benefits, including reduced curvature, pain relief, and improvements in sexual function. However, these studies involved a limited number of participants, which raises questions about the overall validity and effectiveness of Vitamin E as a treatment for PD.

Evaluating the Efficacy of Vitamin E in Peyronie’s Disease

Placebo-controlled trials have shown limited evidence for the effectiveness of Vitamin E in treating Peyronie’s Disease (PD), including pain relief, when compared to placebo groups.

Vitamin E has also been studied in combination with other agents for PD, but the results have been inconsistent. Despite its common use, the overall evidence supporting Vitamin E’s efficacy in PD is limited and generally of poor quality.

Additionally, in broader medical research, Vitamin E has few proven therapeutic uses beyond treating vitamin E deficiency, a condition that is relatively rare.