an illustration on the process of how plaque forms in Peyronie's Disease

Peyronie's Plaque

If you believe you have developed Peyronie's Disease (PD) have a bent penis and because of it suffer pain during sexual intercourse or, cause pain to your partner, we recommend that you visit us to discover what the extent of your Peyronie's plaque problem is.

Don't worry, PD affects approximately 9% of males, most often men in middle age, and is not only physically damaging but can be psychologically damaging too, impacting confidence, mental health, and quality of life. Peyronie's disease is the result of a problem in the way the body heals wounds.





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Peyronie's Plaque Formation and its Impact on the Penis

Peyronie's Disease usually develops after an injury that causes bleeding inside the penis. These injuries are commonly associated with vigorous sexual activity, sports injuries to the penis, or traumatic masturbation. When the injury heals, scar tissue may form, and a plaque can develop. Over time, these plaques can grow and deform the erect penis, leading to pain and a sharp curvature during erections.


a diagram showing what Peyronie's Disease is and the fibrous plaque that forms and causes it

The penis is composed of three tubes

  • The hollow urethra responsible for carrying urine and semen
  • Two spongy tubes called the corpora cavernosa, which fill with blood during an erection to stiffen the penis.

These three tubes are enclosed in a tough, fibrous sheath known as the tunica albuginea. When plaque forms within this sheath, it reduces its flexibility during the stiffening process, resulting in an abnormal curvature of the erect penis.

This less flexibility is caused by abnormal hard, fibrous lumps (plaques) forming inside the tunica albuginea of the penis and over time, these plaques can grow and deform the erect penis. The curvature of the penis is because scar tissue does not stretch as well as normal tissue around it.

In 70% of cases the plaque forms on the top side of the penis (the dorsal side), and sometimes plaques form that go all the way around the penis. In severe cases, the plaque may collect calcium and become very hard indeed, almost like a bone. This may cause pain during sexual intercourse for both the man and his partner. Over time the curvature caused by Peyronie's plaque can increase.  

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Clinical Research on Peyronie's Plaque Formation

Numerous studies have examined the underlying causes of plaque formation in Peyronie's Disease. Research suggests that the most common trigger for plaque development is microtrauma to the tunica albuginea, which occurs during sexual activity or injuries to the genital area as mentioned earlier.

One study published in the Journal of Sexual Medicine demonstrated that repetitive microtrauma caused by sexual activity is a significant risk factor for Peyronie's Disease. The study found that men reporting more frequent and intense sexual activity were more likely to develop PD and experience more severe symptoms due to plaque formation. This emphasises the importance of recognising sexual habits as potential contributors to PD development.

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a diagram showing how shockwave therapy can be used for treating Peyronie's Disease


Treatment Options and Clinical Approaches

Currently, there is no universally agreed-upon standard treatment for Peyronie's Disease. Some cases of PD may improve over time without intervention.

However, when symptoms persist or worsen, various treatment options are available, depending on the severity of the condition. You can find out more about Peyronie's disease treatment options by following the link.






Shockwave Therapy for Peyronie's Plaque

However, the development of shockwave therapy and especially Focussed Shockwave Therapy (FSWT) has transformed the treatment of Peyronie's plaque.

The treatment is completely non-invasive with the focused shockwaves helping to break up the plaque that has developed in the penis. Simultaneously, the unique combination of therapy's that we have developed also treat Erectile Dysfunction which is a frequent comorbidity with Peyronie's Disease.















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11 Upper Ham Rd, 
Richmond Upon Thames, 
TW10 5LD




MansMatters are specialists in non-invasive, nonsurgical procedures. We do not offer surgery but have professional relationships with leading surgical urologists and andrologists who undertake different types of Peyronie's disease surgery. If you would like to know more about surgical options, then please click here.

Surgical Procedures




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