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Peyronie's Disease & Dupuytren's Disease

A study in the journal Sexual Medicine in 2017 reported that, Peyronie's disease (PD) and Dupuytren Contracture (DC) are often comorbid (if you have one you are more likely to have the other) and are believed to have a similar underlying pathophysiologic mechanism.





a person holding both their hands out, one hand with Dupuytren's Disease and the other without

Understanding Dupuytren's Contracture

You may already know that Dupuytren's Disease is a condition where, over a period of time, one or more fingers become permanently bent in a flexed position. This affects both hands and all fingers, resulting in different degrees of deformity for different fingers.

The condition often develops with a small nodule under the skin of the palm and over time the pain gets worse. The fingers can no longer be straightened, and it becomes very hard for patients to grip items like the handle of a cup or a glass.

Like Peyronie's Disease, Dupuytren's Contracture is a connective tissue disorder, where fibrous plaque develops. With Peyronie's Disease, this causes deformity in erections, but with Dupuytren's Contracture the deformity is in the hand.

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 a person with Dupuytren's Disease in their hand against a black background

Exploring the Connection Between Peyronie's Disease and Dupuytren's Disease

Since the early 1800's it has been recognised that there is a correlation between Peyronie's Disease and Dupuytren's Disease. It is estimated that up to 15% of men who have Dupuytren's Disease will also suffer from Peyronie's Disease.

In a recent study it was found that the prevalence of Peyronie's Disease in men with Dupuytren's Contracture is similar to the prevalence of Dupuytren's Contracture in men diagnosed with Peyronie's Disease.

In the early stages of Dupuyren's Disease, before the fingers become too deformed, extra-corporeal shockwave therapy, can be an effective treatment for many men. Therefore, any patients suffering from Peyronie's or Erectile dysfunction can be considered for this treatment.

Where Dupeytren's is at an advanced stage, we can refer to Professor Carlson in Germany who undertakes combined surgical and shockwave therapy.

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MansMatters are specialists in non-invasive, nonsurgical procedures. We do not offer surgery but have professional relationships with leading surgical urologists and andrologists who undertake different types of Peyronie's disease surgery. If you would like to know more about surgical options, then please click here.

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