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Peyronie's Disease & The Autoimmune System

Men suffering an autoimmune disease are highly likely to develop Peyronie's disease if the immune system attacks cells in the penis. This can lead to inflammation in the penis; scar tissue may form, and this may develop into plaque.





Peyronie's Plaque Formation and its Impact on the Penis

In normal situations, the immune system protects the body from infection by identifying and destroying bacteria, viruses, and other harmful substances.

But with an autoimmune disease, a series of fighter cells attack the good cells. These release proteins called autoantibodies that attack healthy cells.

As a result, men who have an autoimmune disease may develop Peyronie's disease when the immune system attacks cells in the penis which can cause scarring and the development of plaque.

There are more than 80 autoimmune diseases, some like type 1 diabetes attack just one organ: the pancreas, while others such as the ones below can affect different parts of the body.

Please take a few minutes to watch this video about Peyronie's disease and the autoimmune system and continue reading about some of the autoimmune diseases associated with Peyronie's disease that follow.


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Some of the Autoimmune Diseases Associated with Peyronie's Disease


Systemic Lupus Erythematosus (Lupus)

This can affect many parts of the body, including the skin, joints, heart, lungs, kidneys, and brain and cause permanent tissue damage.

If you have lupus, you may vary between having times of illness and times of wellness. Lupus flares can be mild to serious, and do not follow a pattern.


Sjögren's Syndrome

Sjögren's syndrome is a rheumatic disease that affects the glands that make moisture. It most often causes dryness in the mouth and eyes but can also affect joints, tendons, ligaments, bones, and muscles. The signs and symptoms of rheumatic diseases can include redness or heat, swelling, pain, and loss of function.

Behçet's Disease

Behçet's disease can affect different parts of your body and causes inflammation of the blood vessels. If you have the disease, you probably have sores in the mouth or on the genitals. More serious symptoms can include swelling, heat, redness, and pain in the eyes and other parts of the body.

The disease is named after the doctor who first described it, Dr. Hulusi Behçet.





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MansMatters are specialists in non-invasive, nonsurgical procedures. We do not offer surgery but have professional relationships with leading surgical urologists and andrologists who undertake different types of Peyronie's disease surgery. If you would like to know more about surgical options, then please click here.

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