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Peyronie's Disease Treatment Options

Exploring Non-Surgical Treatment Options

Choosing the right therapy to treat Peyronie's Disease (PD) is crucial. Traditionally, the only treatment available was invasive surgery.

But today there are a range of successful treatments that can provide the desired results without the need for life-changing surgery. These are outlined below and can be discussed with your MANSMATTERS consultant. 




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a diagram depicting what shockwave therapy entails for Peyronie's Disease

Focused Shockwave Therapy for Peyronie's disease

This is now the gold standard non-invasive Peyronie's disease therapy option, and used in conjunction with EMTT, Nanovi, and our other treatment therapies significantly improves Peyronie's disease without the need for surgery.

A technology pioneered to break up kidney and gallstones now breaks ups and clears plaque in the penis. It is a non-invasive, low pain treatment, and has given many men straighter penises after just a few weeks. A beneficial side effect is stronger erections and more spontaneous natural erections.  

We have treated hundreds of men with PD with our multi-modal shockwave and complementary technologies treatment programme, and you can read some of their reviews on our Peyronie's Disease Case Studies page and further handwritten copies when you visit our clinic. 

Whilst the majority of patients experience immediate improvements after the initial programme of treatment, Peyronie's Disease is a very stubborn condition and in some instances is resistant to all non-invasive treatments and non-surgical treatments.

More on Shockwave Therapy






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Prescribed Medication


Your doctor or urologist may prescribe oral medication or topical treatments applied externally to relieve penile pain, but none of these treatments will stop the progression of PD. There is some evidence that in 10% of cases where men are suffering minor PD, their condition may go away naturally, or they may be left with minor penis curvature.


a diagram showing how a penile pump works as a treatment for Peyronie's Disease


Peyronie's Disease and Medical Vacuum Pumps

This involves a series of penis stretching exercises and the use of a vacuum pump twice a day for 10-minutes each time to strengthen the penis and reduce the bend. Mechanical modelling is used in conjunction with Xiapex Injection therapy, will break down the plaque in the penis.

You can find out more about Peyronie's Disease & Penile Vacuum Pumps by following the link.

a doctor preparing a syringe in a vial of liquid for an injection


PD Injections


There are no medically approved injections to treat PD in the UK, though in other parts of the world there are. In the USA the Food and Drug Administration have approved the use of a drug that contains an enzyme, collagenase.

This is injected directly into the plaque in the penis to destroy it and reduce the curvature.





Get a free phone consultation to discuss our Peyronie's disease treatments




a magnetolith EMTT device for treatment for Peyronie's Disease



Extracorporeal Magneto Transduction Therapy (EMTT®) offers another non-invasive approach to address various types of pain and injury. Its remarkable potential extends to improving men's sexual health, specifically targeting conditions such as Peyronie's Disease, Erectile Dysfunction (ED), and Chronic Pelvic Pain Syndrome (CPPS).

Within our comprehensive treatment protocols, the inclusion of this ground-breaking therapy has become an essential part of our treatment package.

a three dimensional illustration of a NanoVi device to help with Peyronie's Disease treatments


Introducing the NanoVI Exo

NanoVi® helps in the repair cell damage and in the repair of DNA caused by lifestyle, age, and the types of food you eat. It does this by boosting your immune system, and at the same time improving your energy, and slowing the aging process.

NanoVi® does this non-invasively and without using harmful chemicals while helping to repair the endothelial functions in the penis as well as in the prostate area.


the logo for E-Shot, one of the treatments recommended by MansMatters for Peyronie's Disease


The E-Shot™

This non-surgical and painless procedure ensures a safe experience for our patients that takes about thirty minutes to conduct. The treatment is administered at our clinic, simultaneously with other procedures shown here to amplify the overall effectiveness and long-term outcomes of our approach.

To perform the E-Shot™, we extract a small quantity of blood from your body and isolate the vital components that play a role in your natural healing processes. These potent elements are then injected directly and painlessly into your penile tissues, promoting rejuvenation and optimal function.

The E-Shot™ is a well-established medical treatment designed to invigorate the penis by stimulating the growth of new blood vessels and tissue, ultimately rejuvenating the organ and heightening sensitivity within it.

a diagram highlighting how stem cell therapy works for Peyronie's Disease treatment


Stem Cell Therapy

Stem cell therapy holds significant promise in providing therapeutic solutions for various medical conditions affecting men. One area where stem cell therapy may be beneficial is in the treatment of Peyronie's disease.

Stem cells, thanks to their unique regenerative properties, have the potential to repair damaged blood vessels and promote tissue regeneration in the penile region. By injecting stem cells into the affected area, it is believed that they can enhance blood vessel formation and improve erectile function, offering hope for men dealing with PD.






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Peyronie's Disease Surgery

Surgery is the most extreme and life-changing of the Peyronie's disease treatment options. Prior to Focused shockwave therapy, it was the only option for many men.



a diagram highlighting how penile implants would work on a person's body


Penile Implants

Penile implants have been used to treat severe cases of PD and has been commonly used when patients experience both PD and ED.

The implant is inserted within the penis and is operated by a mechanical pump that is used to create an erection. Normal, natural, and spontaneous erections can no longer be achieved, and penis sensitivity and penile length is reduced depending on what prothesis is used.


a diagram showcasing what a surgical graft looks like as a treatment for Peyronie's Disease

Surgical Graft

This surgery has been the procedure for men with complex or severe penile curvature and can only be performed at the stable, chronic stage of PD.

It entails cutting out most of the fibrous plaque and replacing it with an animal or synthetic graft patch to fill the gap. The nerves at the top of the penis or Urethra are dissected prior to the main operation and replaced when surgery is complete.

Grafting procedures are normally carried out where there is severe curvature and the starting penile length is too short, to undertake penile plication. This surgery carries a risk of post-operative erectile dysfunction and a loss of sensitivity in the penis. Post op patients are required to undertake penile stretching and take medication.

The journal Translational Andrology & Urology advise that patients offered this treatment should be advised about its adverse effects and negative outcomes, such as persistent or recurrent curvature, diminished sensation at the glans penis, diminished erectile function, or penile shortening.

More About Surgical Grafts 


a diagram showing the process of penile plication as treatment for Peyronie's Disease

Surgery – Penile Plication

Penile Plication or Nesbitt technique surgery is normally undertaken with patients who don't also suffer ED as well and experience a moderate curvature of less than 60 degrees.

This procedure can only be performed in the stable chronic phase of PD. It involves shortening the long side of the penis (as experienced when erect) to match the side where the fibrous plaque is located. A patient will experience a 1 cm loss in overall penile length for every 15 degrees curvature. This can result in a shortening of the penis length by as much as 5 cm.

In addition to accepting loss in penile length, many patients complain that sutures and knots in the penis are uncomfortable.





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Download the Simple Guide to Peyronie's Disease

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32 Beauchamp Place, 


11 Upper Ham Rd, 
Richmond Upon Thames, 
TW10 5LD




MansMatters are specialists in non-invasive, nonsurgical procedures. We do not offer surgery but have professional relationships with leading surgical urologists and andrologists who undertake different types of Peyronie's disease surgery. If you would like to know more about surgical options, then please click here.

Surgical Procedures




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