Peyronie’s disease is a progressive condition that can lead to penile curvature, discomfort and impaired function. We offer specialist Peyronie’s disease treatment in London, focusing exclusively on non-surgical technologies that support tissue recovery, improve blood flow and address curvature without the need for invasive procedures.
At MansMatters, our approach combines four clinically proven therapies, each selected to match the stage and severity of your condition. All treatments are non-invasive, medically directed and delivered as part of a comprehensive conservative management plan tailored to your needs.
Non-Surgical Peyronie’s Disease
Treatments We Offer
Each of the following treatments targets a different aspect of Peyronie’s disease. In the majority cases, a combination of therapies is recommended to achieve the best possible outcomes. All treatment protocols are determined following a thorough clinical assessment.
Focused Shockwave Therapy for Peyronie's disease
Focused Shockwave Therapy delivers high-energy acoustic waves directly into the fibrotic tissue responsible for penile curvature. This targeted energy stimulates localised microtrauma, which in turn activates a regenerative response. The treatment also promotes angiogenesis (formation of new blood vessels), which is essential for tissue recovery and erectile function.
Unlike radial wave devices commonly used in general practices, this method uses focused energy, allowing for deeper penetration and precise targeting of the affected areas. It is typically delivered across multiple sessions as part of a structured treatment protocol.
Extracorporeal Magneto Transduction Therapy (EMTT)
EMTT delivers high-intensity pulsed magnetic fields to stimulate cellular function and support the body’s repair mechanisms. The technology works at a higher frequency than standard PEMF devices, making it more effective in treating deeper tissues.
EMTT is used to improve microcirculation, modulate inflammation and accelerate cellular turnover in affected areas. It is often paired with Focused Shockwave Therapy to strengthen treatment outcomes and promote long-term tissue stability.
NanoVi Exo
NanoVi Exo is a supportive therapy that enhances the body’s natural ability to repair oxidative damage, a factor closely linked to the progression of Peyronie’s disease. The system emits a patented signal that influences protein folding and cellular repair, contributing to improved tissue quality and function.
It is particularly suited to men presenting with chronic inflammation or generalised tissue stress and may be used alongside physical therapies to support a more regenerative internal environment.
E-Shot
The E-Shot™ is a non-surgical procedure designed to be painless and safe, typically taking about thirty minutes to perform at our clinic. This treatment can be conducted alongside other procedures to enhance overall effectiveness and support long-term outcomes.
During the E-Shot™, a small quantity of blood is drawn from your body, and its components, which are believed to play a role in natural healing processes, are isolated. The blood is processed through a centrifuge to isolate its healing components and undergo photoactivation to release growth factors. These components are then gently injected into the penis, aiming to support rejuvenation and enhance function. We also incorporate shockwave therapy and EMTT to enhance the overall treatment.
This medical treatment is intended to promote the growth of new blood vessels and tissue, potentially revitalising the area and increasing sensitivity. For personalised advice and to see if the E-Shot™ is suitable for you, we recommend consulting with our healthcare professionals.
Medical Vacuum Pumps
Vacuum therapy promotes tissue expansion through negative pressure, encouraging blood flow and tissue flexibility. This is a well-established method used in the management of both Peyronie’s disease and erectile dysfunction.
Our clinic provides medical-grade vacuum devices, selected for their safety, consistency and ease of use. When incorporated into a broader treatment plan, they can help reinforce physical changes and support penile length and function over time.
Common Peyronie's Disease Treatments
Pills for Peyronie's Disease
Your doctor or urologist may prescribe pills or topical treatments applied externally to relieve pain, but none of these treatments will stop the progression of PD. There is some evidence that in 10% of cases where men are suffering minor PD, their condition may go away naturally, or they may be left with minor curvature.
Peyronie's Disease and Medical Vacuum Pumps
This treatment involves a series of stretching exercises using a medical vacuum pump for 10 minutes twice a day, aimed at strengthening the penis and potentially reducing curvature. It is important to consult with a healthcare professional to determine the best treatment approach for individual circumstances. You can find out more by following the link.
Peyronie's Disease Injections
Currently, there are no medically approved injections for treating Peyronie’s Disease (PD) in the UK.
However, in the USA, the Food and Drug Administration (FDA) has approved a drug that contains an enzyme that is injected directly into the plaque to help reduce curvature.
Peyronie's Disease Surgery
At MansMatters, we offer non-invasive treatments designed to treat Peyronie’s disease by improving blood flow, breaking down scar tissue and enhancing erectile function. Unlike surgical procedures, our multi-modal approach aims to restore natural function without the risks associated with invasive treatments.
Implants
Implants are a treatment option for severe cases of Peyronie’s Disease, particularly for patients who may also experience erectile dysfunction (ED). The implant is surgically inserted into the penis and is operated by a mechanical pump, allowing the user to achieve an erection when desired. It is important to note that while implants can provide a functional solution for achieving rigidity, they may affect the ability to achieve natural erections, and sensitivity and length may vary based on the type of prosthesis used. Patients should discuss with their healthcare provider to understand the benefits and limitations of this treatment option.
Surgical Graft
Surgical grafting is a procedure typically considered for men with complex or severe curvature of Peyronie’s Disease. This surgery is performed at a stable stage of the condition. The procedure involves excising the fibrous plaque and replacing it with a graft, which can be made from animal or synthetic materials to fill the resulting gap. During the surgery, the nerves near the penis and urethra may be carefully mobilized to minimize disruption and are reconnected at the end of the procedure. The goal of this surgery is to improve curvature and restore function, offering a potential solution for those with significant symptoms.
The journal Translational Andrology & Urology advises that patients considering surgical grafts for Peyronie’s Disease should be informed about potential adverse effects and outcomes. These may include persistent or recurrent curvature, changes in sensation, altered erectile function, or possible penile shortening
Surgery – Plication
Plication, or the Nesbitt technique, is typically considered for patients with moderate curvature of less than 60 degrees who do not experience erectile dysfunction. This procedure is performed during the stable chronic phase of Peyronie’s Disease. It involves shortening the longer side of the penis to align with the side affected by fibrous plaque. Patients may experience a reduction in overall length, which can be significant, with reports of shortening by several centimeters.
While many patients find this surgery beneficial for correcting curvature, it is important to discuss potential outcomes, including the possibility of changes in penile length and discomfort from sutures used during the procedure.
Why We Focus Exclusively on
Non-Surgical Treatments
For many men, non-surgical options represent a clinically effective pathway that avoids the risks associated with surgery. Our technologies are:
- Non-invasive, with no need for anaesthetic, incisions, or implants
- Based on evidence and used within structured clinical protocols
- Suitable for both acute and stable phases of Peyronie’s disease
- Capable of addressing curvature, function and tissue quality concurrently
These treatments are designed for men who are seeking results without compromising penile integrity or undergoing lengthy recovery periods.
Understanding Surgical and Medication-Based Alternatives
Surgical options — including plication, nesbitt technique, grafting, or penile prosthesis implantation — are typically reserved for severe or unresponsive cases. While surgery may correct curvature, it carries inherent risks such as penile shortening, altered sensation, or complications with erectile function.
Similarly, medication-based interventions such as oral supplements (Vitamin E, Potaba) or enzymatic injections offer limited efficacy when used in isolation. Current research suggests that conservative therapies yield better results when started early and guided by a specialist-led plan.
At our clinic, the emphasis is placed on restoring function without surgical disruption, using non-invasive technologies backed by robust clinical reasoning.
Book a Private Consultation Today
If you’re experiencing symptoms of Peyronie’s disease or seeking specialist advice, our clinic is here to help. We offer a calm, discreet environment, with clear communication and personalised care at every step.
Take the first step — book a consultation with our Peyronie’s disease clinic today.
FAQs
Frequently Asked Questions
What is the best treatment for Peyronie’s disease?
The best treatment depends on the stage and severity of the condition. At our London clinic, we use a combination of non-surgical therapies, including focused shockwave therapy, EMTT, NanoVi Exo and medical vacuum pumps to support structural recovery and reduce curvature.
How effective is Focused shockwave therapy for Peyronie’s disease?
Focused shockwave therapy can help reduce plaque formation, improve blood flow and alleviate discomfort. It is most effective in stable-phase Peyronie’s and is often used alongside other regenerative technologies.
Can Peyronie’s disease be treated without surgery?
Yes. Many men respond well to conservative, non-invasive therapies when treatment is started early. Our approach avoids surgical risks while addressing curvature and function through advanced physical and regenerative modalities.
Do vacuum pumps help Peyronie’s disease?
Medical vacuum devices support tissue stretching and improve circulation. They are commonly used to maintain or enhance gains achieved through other non-surgical treatments and may assist with penile flexibility.
What happens if Peyronie’s disease is left untreated?
If left untreated, Peyronie’s disease may stabilise or progress, leading to worsening curvature, discomfort and potential erectile dysfunction. Early clinical assessment allows for timely, non-surgical intervention.
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